晏石娟，博士，研究员，研究生导师。现任广东省农业科学院农业生物基因研究中心副主任、广东省农作物种质资源保存与利用重点实验室副主任。广东省科技创新青年拔尖人才。德国马普植物分子生理研究所和美国康奈尔大学生物技术研究所访问学者。

　　主要从事代谢调控共性技术研发，重点以玉米和黄曲霉菌为对象，开展营养物质和真菌毒素合成的代谢调控研究。主持承担了国家自然科学基金、国家转基因重大专项子课题、国家重点研发计划项目子课题、广东省重点研发计划项目等科研项目29项，合同总经费2500余万元。并牵头建设了1个广东省国际合作基地。

　　研究成果共发表论文126篇（SCI文章86篇），其中以第一或通讯作者（含共同）身份在《Nature Genetics》、《Nature Communications》、《Molecular Plant》、《Trends in Plant Science》、《Science Bulletin》等期刊发表学术论文共62篇（SCI论文46篇）。授权国家专利32件（其中发明专利共26件）。参编著作1部。

　　一、学术论文代表作（#为第一作者；*为通讯作者）：

　　(1) Shaowen Wu^#, Jintao Xu^#, Lingpeng Zhan ^#, Rulei Li, Hualian Mo, Wenjie Huang, Yarong Zhao, Shaohui Huang, Guanbo Wang*, Shijuan Yan*. Conformational Dynamics-Driven Engineering of Nanobody Biosensor for Enhanced Detection of Ochratoxin A. Journal of Agricultural and Food Chemistry. 2026. 125(2): e70693.

　　(2) Wenyang Zhang^#, Yanjiao Wang^#, Kainan Xu, Wenyan Li, Yan Wei, Shaowen Wu, Mingyang Ye, Yuanyuan Chen, Wenjie Huang, Yang Li, Jianbin Lai, Alisdair R. Fernie, Shijuan Yan*. Temporal dynamics of protein phosphorylation and S-nitrosylation direct maize seed germination programs. Plant Journal. 2026, 126: e70835.

　　(3) Kun Li^#, Yongtao Yu^#, Shijuan Yan^#, Wenqiang Li^#, Jieting Xu, Gaoke Li, Wu Li, Jianhua Liu, Xitao Qi, Wenjie Huang, Qunjie Zhang, Qian Kong, Yingni Xiao, Nan Zhang, Jingyun Luo, Lu Chen, Wenguang Zhu, Tianxiang Wen, Lihua Xie,Yuliang Li, Wenjia Lu, Chunyan Li, Songtao Gui, Yingjie Xiao, Ning Yang, Lin Zhuo, Alisdair R. Fernie, Jianguang Hu* and Jianbing Yan*. Multi-omics analyses reveal the flavor code of sweet corn. Nature Genetics. 2025, 57: 2842-2851.

　　(4) Shaowen Wu^#, Fenghua Wang^#, Weijie Zhou, Xinze Zhang, Lingpeng Zhan, Wenyang Zhang, Wenning Wang, Wolun Zhang, Shaohui Huang, Alisdair R. Fernie, Zhijun Liu*, Shijuan Yan*. Conformational Plasticity of Disordered Regions Enables Sequence-Diverse DNA Recognition by Transcription Factor AflR. Nature Communications. 2025. 16: 8861.

　　(5) Wenyang Zhang^#, Yanjiao Wang^#, Wenyan Li, Shaowen Wu, Yuanyuan Chen, Mingyang Ye, Wenjie Huang, Alisdair R. Fernie, Shijuan Yan*. A novel proteomics workflow for simultaneous analysis of protein phosphorylation and S-nitrosylation.ABIOTECH.2025, 6: 452-465.

　　(6) Shaowen Wu, Sheng Zhang, Chun-Ming Liu, Alisdair R. Fernie, Shijuan Yan*. Recent Advances in Mass Spectrometry-based Protein Interactome Studies. Molecular & Cellular Proteomics. 2025, 24(1), 100887

　　(7) Yaoyao Li, Wenjie Huang, Huijun Gao, Ganjun Yi, Shijuan Yan*. Regulation of Starch Metabolism in Banana Fruit: Mechanisms Shaping the Nutritional Quality. Current Opinion in Plant Biology. 2025, 84,102698.

　　(8) Shaowen Wu^#, Ke Feng^#, Jinlu Niu^#, Jintao Xu, Hualian Mo, Xiaoman She, Shang-Bo Yu *, Zhan-Ting Li, Shijuan Yan*. Acyclic Cucurbit[n]uril-Enabled Detection of Aflatoxin B1 via Host-Guest Chemistry and Bioluminescent Immunoassay. Toxins. 2025,17,104.

　　(9) Jingyun Luo^#, Chunmei He^#, Shijuan Yan^#, Chenglin Jiang, An Chen, Wenjie Huang, Kun Li, Yongli Zhu, Songtao Gui, Ning Yang, Yingjie Xiao, Shenshen Wu, Tieshan Liu, Fajun Zhang, Juan Wang, Yanhua Yang, Haiyan Wang, Wenyu Yang, Wenqiang Li, Lin Zhuo, Alisdair R. Fernie, Junpeng Zhan, Liming Wang*, Jianbing Yan*. A metabolic roadmap of waxy corn flavor.  Molecular Plant.2024, 17(12): 1883-1898.

　　(10) Jing Huang^#, Xueni Fan ^#, Siyu Chen, Mengyu Chen, Tingyu Yang, Ying Zhang, Xin Li, Dingmei Dai, Wenjie Huang, Dong Ruan, Shijuan Yan*, Xiaodan Huang*. Higher Polyphenol Content and Bioactivities of Freeze-dried Lycium ruthenicum Fruit and its Impact on Gut Microbiota Modulation. Food Science and Human Wellness. 2025. 14: 9250233.

　　(11) Xiumei Li^#, Qinjian Liu^#, Hongbo Li, Yuanyuan Chen, Zhongjian Chen, Shengen He, Jun Liu*, Shijuan Yan*. Pretreatment with Nano-silver extends the post-harvest longevity of gladiolus cut flowers by reducing free water mobility. Horticultural Plant Journal. 2025. 11(1): 377-388.

　　(12) Zhibin Yin, Wenjie Huang, Kun Li, Alisdair R.Fernie*, Shijuan Yan*. PERSPECTIVE: Adances in Mass Spectrometry Imaging for Plant Metabolomics- expanding the analytic toolbox. Plant Journal. 2024, 119(5): 2168-2180.

　　(13) Qing Liu, Lanlan Zhang, Shuwei Lyu, Hang Yu, Wenjie Huang, Liqun Jiang, Jing Zhang, Bingrui Sun, Xingxue Mao, Pingli Chen, Junlian Xing, Wenfeng Chen, Zhilan Fan, Shijuan Yan^*, Chen Li^*. UDP-glycosyltransferase OsUGT706D2 positively regulates cold and submergence stress tolerance in rice. Crop Journal. 2024. 12: 732-742.

　　(14) Shaowen Wu^#, Jintao Xu^#, Wenxing Chen, Fenghua Wang, Xiaoliang Tan, Xinlu Zou, Weijie Zhou, Wenjie Huang, Yixiong Zheng, Shihua Wang, Shijuan Yan*. Protein nanoscaffold enables programmable nanobody-luciferase immunoassembly for sensitive and simultaneous detection of aflatoxin B1 and ochratoxin A. Journal of Hazardous Materials. 2024, 462, 132701.

　　(15) Fenghua Wang, Jinlu Niu, Maohua Yang, Weijie Zhou, Wenjie Huang, Zhaofu Chen, Yuanyuan Chen, Dongdong Wang, Jun Zhang*, Shaowen Wu*, Shijuan Yan*. Structure-Guided Discovery of Novel AflG Inhibitors for Targeted Prevention of Aflatoxin Contamination. Frontiersin Microbiology. 2024, 15: 1425790.

　　(16) Zhou Heng, Xiaowan Xu, Xiaomei Xu, Ying Li, Hengming Wang, Lei Liu, Zhenxing Li, Zhiliang Li, Qian You, Baojuan Sun, Chao Gong, Wenjie Huang, Shijuan Yan*, Tao Li*. Integrated transcriptomic and metabolomic analysis of chili pepper fruits provides new insight into the regulation of the branched chain esters and capsaicin biosynthesis. Food Research International. 2023. 169: 112856.

　　(17) Shaowen Wu, Wenjie Huang, Fenghua Wang, Xinlu Zou, Xuan Li, Chun-Ming Liu, Wenyang Zhang,Shijuan Yan*. Integrated metabolomic and lipidomic analyses suggest the temperature-dependent lipid desaturation promotes aflatoxin biosynthesis in Aspergillus flavus. Frontiersin Microbiology. 2023. 14:1137643.

　　(18) Cheng Li^#, Wenjie Huang^#, Xiaoxu Han^#, Guohua Zhao, Wenyang Zhang, Weijun He, Bao Nie, Xufeng Chen, Taijie Zhang, Wenhui Bai, Xiaopeng Zhang, Jingjing He, Cheng Zhao, Alisdair Fernie, Xiaohan Yang*, Shijuan Yan*, Li Wang*. Diel dynamics of multi-omics in elkhorn fern provides new insights into early CAM evolution. Plant Communications.2023. 4(5):100594. 

　　(19) Zhiqiang Wang, Wenyang Zhang, Wenjie Huang, Biao A, Shuang Lin, YingWang, Shijuan Yan*, Shaohua Zeng*. Salt stress affects the fruit quality of Lycium ruthenicum Murr. Industrial Crops & Products.2023. 193: 116240

　　(20) Zhibin Yin, Wenjie Huang, Alisdair R. Fernie* andShijuan Yan*. Mass spectrometry imaging techniques: a versatile toolbox for plant metabolomics. Trends in Plant Science. 2023. 28(2): 250-251.

　　(21) Ou Sheng^#, Zhibin Yin^#, Wenjie Huang^#, Mengyu Chen, Mingyi Du, Qian Kong, Alisdair R. Fernie, Ganjun Yi*, and Shijuan Yan*. Metabolic profiling reveals genotype associated alterations in carotenoid content during banana postharvest ripening. Food Chemistry. 2023. 403:134380.

　　(22) Shaowen Wu^#, Qunjie Zhang^#, Wenyang Zhang^#, Wenjie Huang, Qian Kong, Qinjian Liu, Wenyan Li, Xinlu Zou, Chun-Ming Liu, Shijuan Yan*. Linolenic acid-derived oxylipins inhibit aflatoxin biosynthesis in Aspergillus flavus through activation of imizoquin biosynthesis. Journal of Agricultural and Food Chemistry. 2022. 70, 15928−15944.

　　(23) Wenyang Zhang^#, Cheuk-Kuen Lai^#, Wenjie Huang, Wenyan Li, Shaowen Wu, Qian Kong, Alan C. Hopkinson, Alisdair R. Fernie, K. W. Michael Siu* and Shijuan Yan*. An eco-friendly, low-cost, and automated strategy for phosphoproteome profiling. Green Chemistry. 2022. 24, 9697-9708.

　　(24) Shijuan Yan^#,*, Qing Liu^#, Wenyan Li, Jianbing Yan, Alisdair R. Fernie*. Raffinose family oligosaccharides: crucial regulators of plant development and stress responses. Critical Reviews in Plant Science. 2022. 41(4): 286-303.

　　(25) Shijuan Yan, Ruchika Bhawal, Zhinbin Yin, Theodore W. Thannhauser and Sheng Zhang*. Recent advances in proteomics and metabolomics in plants. Molecular Horticulture. 2022. 2:17

　　(26) Qing Liu, Jierong Ding, Wenjie Huang, Hang Yu, Shaowen Wu, Wenyan Li, Xingxue Mao, Wenfeng Chen, Junlian Xing, Chen Li*, Shijuan Yan*. OsPP65 negatively regulates water and salt stress responses through regulating the phytohormone and raffinose family oligosaccharide metabolic pathways in rice. Rice. 2022. 15:34

　　(27) Zhibin Yin^#, Tao Dong^#, Wenjie Huang^#, Mingyi Du, Dong Chen, Alisdair R. Fernie, Ganjun Yi*, and Shijuan Yan*. Spatially resolved metabolomics reveals variety-specific metabolic changes in banana pulp during postharvest senescence. Food Chemistry X. 2022. 15:100371. 

　　(28) Bingxian Chen^#, Hua Fu^#, Jiadong Gao^#, Yixin Zhang, Wenjie Huang, Zhongjian Chen, Qi Zhang, Shijuan Yan* and Jun Liu*. Identification of Metabolomic Biomarkers of Seed Vigor and Aging in Hybrid Rice.Rice. 2022. 15(1): 7-19. 

　　(29) Mengyu Chen^#, Wenjie Huang^#, Zhibin Yin, Wenyang Zhang, Qian Kong, Shaowein Wu, Wenyan Li, Zhao Bai, Alisdair R. Fernie, Xiaodan Huang*, Shijuan Yan*. Environmentally-driven metabolite and lipid variations correspond to altered bioactivities of black wolfberry fruit.Food Chemistry. 2022. 372(2022): 13142-13152. 

　　(30) Shaowen Wu, Wenyang Zhang, Wenyan Li, Wenjie Huang, Qian Kong, Zhongjian Chen, Wenkang Wei, Shijuan Yan*. Dissecting the Protein Dynamics Coupled Ligand Binding with Kinetic Models and Single-Molecule FRET. Biochemistry. 2022. 61:433-445.

　　(31) Zhibin Yin, Mingyi Du, Dong Chen, Wenyang Zhang, Wenjie Huang, Xinzhou Wu*, Shijuan Yan*. Rapid structural discrimination of IgG antibodies by multicharge-state collision-induced unfolding. RSC Advance. 2021. 11(58): 36502-36510.

　　(32) Shijuan Yan^#,*, Qing Liu^#, Thomas Naake, Wenjie Huang, Mengyu Chen, Qian Kong, Sheng Zhang, Wenyan Li, Xuan Li, Qinjian Liu, Jianyuan Yang, Alisdair R. Fernie*, Bin Liu*. OsGF14b modulates defense signaling pathways in rice panicle blast response. TheCrop Journal. 2021. 9(4): 725-738.

　　(33) Hong Wang, Xinbo Guo*, Quan Li, Yanyan Lu, Wenjie Huang, Fangyuan Zhang, Ling Chen, Rui Hai Liu, ShijuanYan*. Integrated Transcriptomic and Metabolic Framework for Carbon Metabolism and Plant Hormones Regulation in Mung Bean (Vigna radiata) during Post-Germination Seedling Growth. Scientific Reports. 2020. 10(1): 3745-3756.

　　(34) Yushan Huang, Zuhong Zhang, Tianchun Hou, Jingfang Shi, Wenjie Huang, Zhao Bai, Danfeng Long, Xiangdan Huang*, Shijuan Yan*. Antibiotic burden of school children from Tibetan, Hui, and Han groups in the Qinghai–Tibetan Plateau. PLoS ONE. 2020. 15(2): 1-16.

　　(35) Hai Wang^#, Shijuan Yan^#, Hongjia Xin, Wenjie Huang, Hao Zhang, Shouzhen Teng, Ya-Chi Yu, Alisdair R. Fernie, Xiaoduo Lu, Pengcheng Li, Shengyan Li, Chunyi Zhang, Yong-Ling Ruan, LiQing Chen*, Zhihong Lang*. A Subsidiary Cell-Localized Glucose Transporter Promotes Stomatal Conductance and Photosynthesis. ThePlant Cell. 2019. 31(6): 1328–1343. 

　　(36) Zhou Heng^#, Ou Sheng^#, Wenjie Huang, Sheng Zhang, Alisdair R. Fernie, Ievgen Motorykin, Qian Kong, Ganjun Yi^*, Shijian Yan*. Integrated proteomic and metabolomic analysis suggests high rates of glycolysis are likely required to support high carotenoid accumulation in banana pulp. Food Chemistry. 2019. 297(2019): 125016-125025. 

　　(37) Hualing Wu^#, Wenjie Huang^#, Zhongjian Chen^#, Zhuang Chen, Jingfang Shi, Qian Kong, Shili Sun, Xiaohui Jiang, Dong Chen*, Shijuan Yan*. GC-MS-based metabolomic study reveals dynamic changes of chemical compositions during black tea processing. Food Research International. 2019. 120: 330-338.

　　(38) Wenjie Huang^#, Qiongju Qiu^#, Mengyu Chen, Jingfang Shi, Xiaodan Huang, Qian Kong, Danfeng Long, Zhuang Chen*, Shijuan Yan*. Determination of 18 antibiotics in urine using LC-QqQ-MS/MS. Journal of Chromatography B. 2019. 1105: 176-183.

　　(39) Jingfang Shi^#, Wenjie Huang^#, Zhuang Chen, Shili Sun, Limin Xiang, Qian Kong, Xiaohui Jiang, Dong Chen*, Shijuan Yan*. Characterization of volatile components of eight FengHuang Dancong manufactured teas and fresh Leaves by HS-SPME coupled with GC-MS. International Journal of Nutrition and Food Sciences. 2018, 7(5):160-172.

　　(40) Qing Liu^#, Shijuan Yan^#, Wenjie Huang, Jianyuan Yang, Jingfang Dong, Shaohong Zhang, Junliang Zhao, TifengYang, Xingxue Mao, Xiaoyuan Zhu*, Bin Liu*. NAC transcription factor ONAC066 positively regulates disease resistance by suppressing the ABA signaling pathway in rice. Plant Molecular Biology. 2018. 98(4-5): 289-302.

　　(41) Shijuan Yan, Wenjie Huang, Jiadong Gao, Hua Fu*, Jun Liu*. Comparative metabolomic analysis of seed metabolites associated with seed storability in rice (Oryza sativa L.) during natural aging. Plant Physiology and Biochemistry. 2018. 127: 590-598.

　　(42) Shijuan Yan^#, Cui Zhu^#, Ting Yu^#, Wenjie Huang, Jianfeng Huang, Qian Kong, Jingfang Shi, Zhongjian Chen, Qinjian Liu, Shaolei Wang, Zongyong Jiang*, Zhuang Chen*. Studying the differences of bacterial metabolome and microbiome in the colon between Landrace and Meihua piglets. Frontiers in Microbiology. 2017. 8: 1812-1826.

　　(43) Qing Liu^#, Shijuan Yan^#, Tifeng Yang, Shaohong Zhang, Yue-qin Chen*, Bin Liu*. Small RNAs in regulating temperature stress response in plants. Journal of Integrative Plant Biology. 2017. 11(59):774-791.

　　(44) Shijuan Yan^#, Jiangfeng Huang^#, Zhongjian Chen, Zongyong Jiang, Xue Li, Zhuang Chen*. Metabonomics in gut microbiota: recent progresses and future challenges. Science Bulletin. 2016. 61(15): 1151–1153.

　　(45) Shijuan Yan, Yating Liang, Jindan Zhang , Zhuang Chen, Chun-Ming Liu*. Autoxidated linolenic acid inhibits aflatoxin biosynthesis in Aspergillus flavus via oxylipin species. Fungal Genetics and Biology. 2015. 81: 229-237.

　　(46) Shijuan Yan, Yating Liang, Jindan Zhang, Chun-Ming Liu*. Aspergillus flavus grown in peptone as the carbon source exhibits spore density- and peptone concentration-dependent aflatoxin biosynthesis. BMC Microbiology. 2012. 12: 106-120.

　　二、联系方式：

　　工作单位：广东省农业科学院农业生物基因研究中心

　　通信地址：广东省广州市天河区金颖路20号创新大楼，510640

　　电话：020－85161425

　　E-mail：yanshijuan@gdaas.cn; shijuan@agrogene.ac.cn